|
Arri is a Consultant at Birmingham Women's Hospital, Senior Lecturer at the University of Birmingham and a Subspecialist in Reproductive Medicine and Surgery. He teaches in various MRCOG, DRCOG and evidence-based medicine (EBM) courses, as well lectures to MSc students at the University of Birmingham. His lectures are invariably interactive, and are based on sound educational principles.
Arri has published over 70 research articles in top medical journals, such as Nature Reviews, BMJ, CMAJ, BJOG, Obstetrics & Gynecology, Fertility & Sterility and Human Reproduction. He has written several book chapters, books and was also the principal author of the RCOG guideline on "The investigation and management of the small for gestational age fetus". He is a Scientific Editor for BJOG.
He holds over £4 million in research grants, and runs an active research programme. In the past, he was commissioned by the West Midlands Deanery to run EBM workshops for SpRs and Consultants across all specialities in the West Midlands Region, and has been commissioned by the European Union to promote EBM to private enterprises that supply to the NHS.
Arri led a team of researchers in setting up a multi-centre randomised trial to evaluate the effects of progesterone in recurrent miscarriages (PROMISE Trial). This trial has recently been funded by the MRC/HTA for £1.2 million. He also supervises several other randomised trials, including: PRINT Trial (Poor Responders Intervention Trial), to assess the effects of three down-regulation regimes on IVF success in women with reduced ovarian reserves; TROPHY Trial (Trial of outpatient hysteroscopy in women with repeated IVF failures), and FIT for IVF Trial (Fibroid Intervention Trial - assessing the effects of myomectomy on IVF outcomes in women with non cavity distorting intramural fibroids)

Publications in medical journals
- Marriott JV, Stec P, El-Toukhy T, Khalaf Y, Braude P, Coomarasamy A.Infertility information on the World Wide Web: a cross-sectional survey of quality of infertility information on the internet in the UK.Hum Reprod. 2008 Mar 27. [Epub ahead of print]
- Hammadieh N, Coomarasamy A, Ola B, Papaioannou S, Afnan M, Sharif K.Ultrasound-guided hydrosalpinx aspiration during oocyte collection improves pregnancy outcome in IVF: a randomized controlled trial.Hum Reprod. 2008 May;23(5):1113-7.
- Cnossen JS, Morris RK, ter Riet G, Mol BW, van der Post JA, Coomarasamy A, Zwinderman AH, Robson SC, Bindels PJ, Kleijnen J, Khan KS. Use of uterine artery Doppler ultrasonography to predict pre-eclampsia and intrauterine growth restriction: a systematic review and bivariable meta-analysis.CMAJ. 2008 Mar 11;178(6):701-11.
- Khairy M, Clough A, El-Toukhy T, Coomarasamy A, Khalaf Y. Antral follicle count at down regulation and prediction of poor ovarian response. RBM Online (in press)
- El-Toukhy T, Sunkara SK, Coomarasamy A, Grace J, Khalaf Y. Outpatient hysteroscopy and subsequent IVF cycle outcome: a systematic review and meta-analysis. RBM Online (in press)
- Khalaf Y, El-Toukhy T, Coomarasamy A, Kamal A, Bolton V, Braude P.Selective single blastocyst transfer reduces the multiple pregnancy rate and increases pregnancy rates: a pre- and postintervention study.BJOG. 2008 Feb;115(3):385-90.
- Sunkara SK, Coomarasamy A, Khalaf Y, Braude P.A three-arm randomised controlled trial comparing Gonadotrophin Releasing Hormone (GnRH) agonist long regimen versus GnRH agonist short regimen versus GnRH antagonist regimen in women with a history of poor ovarian response undergoing in vitro fertilisation (IVF) treatment: Poor responders intervention trial (PRINT).Reprod Health. 2007 Dec 28;4:12.
- Coomarasamy A, Afnan M, Cheema D, van der Veen F, Bossuyt PM, van Wely M.Urinary hMG versus recombinant FSH for controlled ovarian hyperstimulation following an agonist long down-regulation protocol in IVF or ICSI treatment: a systematic review and meta-analysis. Hum Reprod. 2008 Feb;23(2):310-5.
- Sunkara SK, Tuthill J, Khairy M, El-Toukhy T, Coomarasamy A, Khalaf Y, Braude P.Pituitary suppression regimens in poor responders undergoing IVF treatment: a systematic review and meta-analysis. Reprod Biomed Online. 2007 Nov;15(5):539-46. Review. PMID: 18028745
- Rutjes A, Reitsma JB, Coomarasamy A, Khan KS, Bussuyt PMM. Methodological Research in Diagnostic Test: Evaluation of diagnostic tests when there is no gold standard - a review of methods. Archives in Internal Medicine. 2007 (in press)
- Rutjes AW, Reitsma JB, Coomarasamy A, Khan KS, Bossuyt PM. Evaluation of diagnostic tests when there is no gold standard. A review of methods.Health Technol Assess. 2007 Dec;11(50):iii, ix-51.
- Johnson A, El-Toukhy T, Sunkara SK, Khairy M, Coomarasamy A, Ross C, Bora S, Khalaf Y, Braude P.Validity of the in vitro fertilisation league tables: influence of patients' characteristics.BJOG. 2007 Dec;114(12):1569-74.
- El-Toukhy T, Coomarasamy A, Khairy M, Sunkara K, Seed P, Khalaf Y, Braude P.The relationship between endometrial thickness and outcome of medicated frozen embryo replacement cycles.Fertil Steril. 2008 Apr;89(4):832-9.
- Davis J, Chryssafidou E, Zamora J, Davies D, Khan K, Coomarasamy A.Computer-based teaching is as good as face to face lecture-based teaching of evidence based medicine: a randomised controlled trial.BMC Med Educ. 2007 Jul 20;7:23.
- Cheema D, Coomarasamy A, El-Toukhy T.Non-hormonal therapy of post-menopausal vasomotor symptoms: a structured evidence-based review.Arch Gynecol Obstet. 2007 Nov;276(5):463-9.
- Khairy M, Banerjee K, El-Toukhy T, Coomarasamy A, Khalaf Y. Aspirin in women undergoing in vitro fertilization treatment: a systematic review and meta-analysis. Fertil Steril. 2007 May 15
- Thangaratinam S, Ismail K, Sharp S, Coomarasamy A, O'Mahony F, Khan KS, O'Brien S; TIPPS (Tests in Prediction of Preeclamsia's Severity) Review Group. Prioritisation of tests for the prediction of preeclampsia complications: a Delphi survey. Hypertens Pregnancy. 2007;26(1):131-8.
- Yanamandra SR, Redman CW, Coomarasamy A, Varma R. Leiomyoma appearing in the vaginal vault following hysterectomy. J Obstet Gynaecol. 2007 Jan;27(1):91-2.
- Morris RK, Khan KS, Coomarasamy A, Robson SC, Kleijnen J. The value of predicting restriction of fetal growth and compromise of its wellbeing: Systematic quantitative overviews (meta-analysis) of test accuracy literature. BMC Pregnancy Childbirth. 2007 Mar 8;7:3.
- Johnson NP, Bagrie EM, Coomarasamy A, Bhattacharya S, Shelling AN, Jessop S, Farquhar C, Khan KS. Ovarian reserve tests for predicting fertility outcomes for assisted reproductive technology: the International Collaboration of Ovarian Reserve Evaluation protocol for a systematic review of ovarian reserve test accuracy. BJOG. 2006 Dec;113(12):1472-80. Review.
- Khan KS, Coomarasamy A. A hierarchy of effective teaching and learning to acquire competence in evidenced-based medicine. BMC Med Educ. 2006 Dec 15;6:59.
- Zamora J, Abraira V, Muriel A, Khan K, Coomarasamy A. Meta-DiSc: a software for meta-analysis of test accuracy data. BMC Med Res Methodol. 2006 Jul 12;6:31.
- Brook N, Khalaf Y, Coomarasamy A, Edgeworth J, Braude P. A randomized controlled trial of prophylactic antibiotics (co-amoxiclav) prior to embryo transfer. Hum Reprod. 2006 Nov;21(11):2911-5.
- Coomarasamy A, Thangaratinam S, Gee H, Khan KS. Progesterone for the prevention of preterm birth: A critical evaluation of evidence. EJOG. 2006 Dec;129(2):111-8.
- Thangaratinam S, Yanamandra SR, Deb S, Coomarasamy A. Specialist training in obstetrics and gynaecology: a survey on work-life balance and stress among trainees in UK. J Obstet Gynaecol. 2006 May;26(4):302-4.
- Clark TJ, Barton PM, Coomarasamy A, Gupta JK, Khan KS. Investigating postmenopausal bleeding for endometrial cancer: cost-effectiveness of initial diagnostic strategies.BJOG. 2006 May;113(5):502-10.
- Pretlove SJ, Radley S, Toozs-Hobson PM, Thompson PJ, Coomarasamy A, Khan KS. Prevalence of anal incontinence according to age and gender: a systematic review and meta-regression analysis. Int Urogynecol J Pelvic Floor Dysfunct. 2006 Jun;17(4):407-17.
- Thangaratinam S, Ismail KM, Sharp S, Coomarasamy A, Khan KS; Tests in Prediction of Pre-eclampsia Severity review group. Accuracy of serum uric acid in predicting complications of pre-eclampsia: a systematic review.BJOG. 2006 Apr;113(4):369-78.
- Mol BW, Verhagen TE, Hendriks DJ, Collins JA, Coomarasamy A, Opmeer BC, Broekmans FJ. Value of ovarian reserve testing before IVF: a clinical decision analysis. Hum Reprod. 2006 Jul;21(7):1816-23.
- Coomarasamy A, Thornton J, Bossuyt P.Registering protocols for systematic reviews with BJOG. BJOG. 2005 Dec;112(12):1588.
- Coomarasamy A, Connock M, Thornton J, Khan KS. Accuracy of ultrasound biometry in the prediction of macrosomia: a systematic quantitative review.BJOG. 2005 Nov;112(11):1461-6.
- Thornton J, Bossuyt P, Khan KS, Coomarasamy A. Registering protocols for studies of test accuracy with BJOG.BJOG. 2005 Jun;112(6):683..
- Thangaratinam S, Coomarasamy A. Progestational agents to prevent preterm birth: a meta-analysis of randomized controlled trials. Obstet Gynecol. 2005 Jun;105(6):1483-4
- Coomarasamy A, Khan KS. What is the evidence that postgraduate teaching in evidence based medicine changes anything? A systematic review. BMJ. 2004 Oct 30;329(7473):1017.
- Thangaratinam S, Coomarasamy A. Progestational agents to prevent preterm birth: a meta-analysis of randomized controlled trials. Obstet Gynecol. 2005 Jun;105(6):1483-4.
- Thornton J, Bossuyt P, Khan KS, Coomarasamy A. Registering protocols for studies of test accuracy with BJOG. BJOG. 2005 Jun;112(6):683.
- Bullock R, Martin WL, Coomarasamy A, Kilby MD.Prediction of fetal anemia in pregnancies with red-cell alloimmunization: comparison of middle cerebral artery peak systolic velocity and amniotic fluid OD450. Ultrasound Obstet Gynecol. 2005 Apr;25(4):331-4.
- Clark TJ, Ter Riet G, Coomarasamy A, Khan KS. Bias associated with delayed verification in test accuracy studies: accuracy of tests for endometrial hyperplasia may be much higher than we think! BMC Med. 2004 May 11;2(1):18.
- Brealey S, Scally A, Hahn S, Thomas N, Godfrey C, Coomarasamy A. Accuracy of radiographer plain radiograph reporting in clinical practice: a meta-analysis. Clin Radiol. 2005 Feb;60(2):232-41.
- Papaioannou S, Bourdrez P, Varma R, Afnan M, Mol BW, Coomarasamy A. Tubal evaluation in the investigation of subfertility: a structured comparison of tests. BJOG. 2004 Dec;111(12):1313-21.
- Jha S, Coomarasamy A, Chan KK. Ureteric injuries in obstetrical and gynaecological surgery. The Obstetrician & Gynaecologist. 2004 (in press: scheduled for publication in October 2004)
- Chryssafidou E, Arvanitis TN, Khan KS, Coomarasamy A. South Asian health: what is to be done? Skills of evidence based medicine need to be taught. BMJ. 2004 Apr 3;328(7443):839.
- Coomarasamy A, Knox EM, Gee H, Song F, Khan KS. Effectiveness of nifedipine versus atosiban for tocolysis in preterm labour: a meta-analysis with an indirect comparison of randomised trials. BJOG. 2003 Dec;110(12):1045-9.
- Coomarasamy A, Braunholtz D, Song F, Taylor R, Khan KS. Individualising use of aspirin to prevent pre-eclampsia: a framework for clinical decision making. BJOG. 2003 Oct;110(10):882-8. Review.
- Honest H, Coomarasamy A, Bachmann LM, Khan KS. Cervical cerclage for prevention of preterm delivery: meta-analysis of randomized trials. Obstet Gynecol. 2004 Mar;103(3):584-5; author reply 585-6.
- Sorinola O, Olufowobi O, Coomarasamy A, Khan KS. Instructions to authors on case reporting is limited: A review of a core journals list. BMC Med Educ. 2004 Mar 25;4(1):4.
- Coomarasamy A, Taylor R, Khan KS. A systematic review of postgraduate teaching in evidence-based medicine and critical appraisal. Med Teach. 2003 Jan;25(1):77-81.
- Coomarasamy A, Ola B, Gee H, Khan KS. Quality of brief guidelines produced by professional bodies: a study of the 'green-top' guidelines by the UK Royal College of Obstetricians and Gynaecologists. J Obstet Gynaecol. 2003 Sep;23(5):479-83.
- Honest H, Bachmann LM, Coomarasamy A, Gupta JK, Kleijnen J, Khan KS. Accuracy of cervical transvaginal sonography in predicting preterm birth: a systematic review. Ultrasound Obstet Gynecol. 2003 Sep;22(3):305-22.
- Ola B, Afnan M, Papaioannou S, Sharif K, Bjorndahl L, Coomarasamy A. Accuracy of sperm-cervical mucus penetration tests in evaluating sperm motility in semen: a systematic quantitative review. Hum Reprod. 2003 May;18(5):1037-46.
- Bachmann LM, Coomarasamy A, Honest H, Khan KS. Elective cervical cerclage for prevention of preterm birth: a systematic review. Acta Obstet Gynecol Scand. 2003 May;82(5):398-404.
- Jha S, Gee H, Coomarasamy A. Women's attitudes to HIV screening in pregnancy in an area of low prevalence. BJOG. 2003 Feb;110(2):145-8.
- Papaioannou S, Afnan M, Girling AJ, Ola B, Olufowobi O, Coomarasamy A, Sharif K. Diagnostic and therapeutic value of selective salpingography and tubal catheterization in an unselected infertile population. Fertil Steril. 2003 Mar; 79(3):613-7.
- Papaioannou S, Afnan M, Girling AJ, Coomarasamy A, McHugo JM, Sharif K.The potential value of tubal perfusion pressures measured during selective salpingography in predicting fertility. Hum Reprod. 2003 Feb;18(2):358-63.
- Coomarasamy A, Gee H, Khan KS. Low dose acetylsalicylic acid in prevention of pregnancy-induced hypertension and intrauterine growth retardation in women with bilateral uterine artery notches. BJOG. 2002 Dec;109(12):1420-1.
- Coomarasamy A, Knox EM, Gee H, Khan KS. Oxytocin antagonists for tocolysis in preterm labour - a systematic review. Med Sci Monit. 2002 Nov;8(11):RA268-73.
- Papaioannou S, Afnan M, Girling AJ, Coomarasamy A, Ola B, Olufowobi O, McHugo JM, Hammadieh N, Sharif K. Long-term fertility prognosis following selective salpingography and tubal catheterization in women with proximal tubal blockage. Hum Reprod. 2002 Sep;17(9):2325-30.
- Papaioannou S, Afnan M, Girling AJ, Coomarasamy A, Ola B, Olufowobi O, McHugo JM, Hammadieh N, Sharif K. The effect on pregnancy rates of tubal perfusion pressure reductions achieved by guide-wire tubal catheterization. Hum Reprod. 2002 Aug;17(8):2174-9.
- Papaioannou S, Afnan M, Girling AJ, Ola B, Hammadieh N, Coomarasamy A, Sharif K. The learning curve of selective salpingography and tubal catheterization. Fertil Steril. 2002 May;77(5):1049-52.
- Ola B, Afnan M, Sharif K, Hammadieh N, Papaioannou S, Coomarasamy A. Cost-effectiveness of recombinant versus urinary follicle stimulating hormone; whose point of view? Acta Obstet Gynecol Scand. 2001 Dec;80(12):1141-2.
- Papaioannou S, Afnan M, Coomarasamy A, Ola B, Hammadieh N, Temperton DH, McHugo JM, Sharif K. Long term safety of fluoroscopically guided selective salpingography and tubal catheterization. Hum Reprod. 2002 Feb;17(2):370-2.
- Coomarasamy A, Gee H, Publicover M, Khan KS. Medical journals and effective dissemination of health research. Health Info Libr J. 2001 Dec;18(4):183-91.
- Coomarasamy A, Papaioannou S, Gee H, Khan KS. Aspirin for the prevention of preeclampsia in women with abnormal uterine artery Doppler: a meta-analysis. Obstet Gynecol. 2001 Nov;98(5 Pt 1):861-6.
- Coomarasamy A, Latthe P, Papaioannou S, Publicover M, Gee H, Khan KS. Critical appraisal in clinical practice: sometimes irrelevant, occasionally invalid. J R Soc Med. 2001 Nov;94(11):573-7.
- Papaioannou S, Afnan M, Coomarasamy A, Ola B, Hammadieh N, Sharif K. The use of repeat hysterosalpingography. Fertil Steril. 2001 Oct;76(4):849-50.
- Papaionnou S, Afnan M, Ola B, Coomarasamy A, Hammadieh N, Sharif K. Validity of comparisons? Fertil Steril. 2001 Aug;76(2):427-8.
- Coomarasamy A, Van Der Berg D. Open access follow up for inflammatory bowel disease. Ability of any method of follow up to detect cancer must be stated. BMJ. 2000 Jun 24;320(7251):1730.
- Coomarasamy A, Gee H. Reviews in feto-maternal medicine. Advances in Obstetrics and Gynaecology 2001;19: 23-24
- Papaionnou S, Afnan M, Ola B, Coomarasamy A, Sharif K. Modification of the coaxial technique for selective salpingography with measurement of tubal perfusion pressures. Hum Fertil 2003 (in press)
- Coomarasamy A, Gee H, Khan KS, Braunholtz D. Aspirin has clinically significant benefit in high risk groups - Summary NNT can mislead clinicians. eBMJ 21.02.2001 (Also simultaneously published in the Cochrane Database - Identifier: CD000492)
- Coomarasamy A, Gee H. Elective delivery in diabetic pregnant women [letter] Cochrane Database CRG:PREG - Identifier: CD001997
- Coomarasamy A, Ayuk J. How helpful is NHS Direct: postal survey of callers [letter] eBMJ 18.04.2000
- Coomarasamy A, Fisk N, Gee H, Robson SC. Investigation and management of the small for gestational age fetus - RCOG Green Top Guideline No 31, Nov 2002, RCOG, London.
Abstracts
- Kamal NG, Coomarasamy A, Khan KS, Kehoe S, Luesley DM. Diagnostic accuracy of clinical examination of the inguinal lymph nodes in vulval cancer. [29 th British Congress of Obstetrics and Gynaecology, 10-13 th July 2001, Birmingham, UK]
- Kamal NG, Coomarasamy A, Mann C, Watson E, Kehoe S. When does parametrial involvement in cervical cancer dictate post-operative radiotherapy? [29 th British Congress of Obstetrics and Gynaecology, 10-13 th July 2001, Birmingham, UK]
- Papaioannou S, Afnan M, Coomarasamy A, Hammadieh N, Ola B, McHugo J, Sharif K. The learning curve of selective salphingography. [17 th Annual Meeting of European Society of Human Reproduction and Embryology, 1-4 th July 2001, Lausanne, Switzerland]
- Papaioannou S, Afnan M, Coomarasamy A, Hammadieh N, Ola B, McHugo J, Sharif K. Live birth rates after guide-wire tubal recanalization in cases of proximal tubal obstruction. [17 th Annual Meeting of European Society of Human Reproduction and Embryology, 1-4 th July 2001, Lausanne, Switzerland]
- Bullock R, Martin W, Coomarasamy A, Kilby MD. Diagnostic accuracy of middle cerebral artery velocity compared to amniotic fluid optical density to predict fetal anaemia. [British Maternal Fetal Medicine Society, March 2003, York, UK.]
- Honest H, Bachman L, Coomarasamy A, Gupta JK, Khan KS. Cervical ultrasound to predict preterm labour: A systematic quantitative review. [British Maternal Fetal Medicine Society, March 2003, York, UK.]
Book Chapters
Coomarasamy A, Latthe M. Evidence-based Medicine in General Practice in 'Obstetrics and Gynaecology for General Practioners', RCGP Publications, London, 2003.
Coomarasamy A, van der Berg D. Problems in Later Pregnancy in 'Obstetrics and Gynaecology for General Practioners', RCGP Publications, London, 2003.
Coomarasamy A, Kilby MD. Intrauterine Growth Restriction in 'Vignettes for the MRCOG' Quay Books, Wilts, 2003.
Ola B, Coomarasamy A, Sharif K. Bed Rest in In-vitro Fertilisation in 'Evidence-based Infertility Treatment' (Editor: Professor S Daya, in press)
Coomarasamy A, Khan KS. Evidence-based Continuing Medical Education in 'Evidence-based Obstetrics' (Editor: Professor S Daya, in press)
Books
Coomarasamy A, Zamora J, Khan KS. Systematic reviews of tests. RSM Publications. (in press, publication due in Dec 2008)
Clark TJ, Coomarasamy A. OSCEs for MRCOG II. RSM Publications (in Press, due in Oct 2008)
Recent invited talks at international conferences
RCOG, London, UK. Invited to give two lectures ("Evidence based reproductive medicine" & "Long-term outcomes of ART babies") at the BFS/RCOG 5-day Infertility and Assisted Reproduction Course, April 2008
London, UK. Invited to debate the role of progesterone in recurrent miscarriage at the AEPU (Association of Early Pregnancy Units) conference, Nov 2007
Washington, DC, USA. Invited speaker at a USAID meeting on the reduction of maternal deaths and disability in the developing world. July 2007
Barcelona, Spain. Invited speaker on "How to write scientific articles: an editor's perspective". STIRMAS (Subspecialist Trainees in Reproductive Medicine and Surgery) Conference, May 2007.
Krakow, Poland. Invited speaker on 'Meta-analysis of diagnostic data' International Health Technology Assessment Conference, 2004.
Birmingham, UK. Invited speaker on 'Effective teaching of Evidence-based Medicine' International Conference on Enhancing the Education of Doctors and Dentists, 2004.
Dhaka, Bangladesh. Invited speaker on 'Aspirin to prevent pre-eclampsia: an evidence-based appraisal' Developing EBM in the Developing World . Tele-streamed Conference, 2004.
RCOG, London, UK. Invited speaker on 'Guidelines for growth restriction'. International Symposium on In-utero Surveillance (ISIS) Conference. 2003.
|