Arri is a Consultant at Birmingham Women's Hospital, Senior Lecturer at the University of Birmingham and a Subspecialist in Reproductive Medicine and Surgery. He teaches in various MRCOG, DRCOG and evidence-based medicine (EBM) courses, as well lectures to MSc students at the University of Birmingham. His lectures are invariably interactive, and are based on sound educational principles.

Arri has published over 70 research articles in top medical journals, such as Nature Reviews, BMJ, CMAJ, BJOG, Obstetrics & Gynecology, Fertility & Sterility and Human Reproduction. He has written several book chapters, books and was also the principal author of the RCOG guideline on "The investigation and management of the small for gestational age fetus". He is a Scientific Editor for BJOG.

He holds over £4 million in research grants, and runs an active research programme. In the past, he was commissioned by the West Midlands Deanery to run EBM workshops for SpRs and Consultants across all specialities in the West Midlands Region, and has been commissioned by the European Union to promote EBM to private enterprises that supply to the NHS.

Arri led a team of researchers in setting up a multi-centre randomised trial to evaluate the effects of progesterone in recurrent miscarriages (PROMISE Trial). This trial has recently been funded by the MRC/HTA for £1.2 million. He also supervises several other randomised trials, including: PRINT Trial (Poor Responders Intervention Trial), to assess the effects of three down-regulation regimes on IVF success in women with reduced ovarian reserves; TROPHY Trial (Trial of outpatient hysteroscopy in women with repeated IVF failures), and FIT for IVF Trial (Fibroid Intervention Trial - assessing the effects of myomectomy on IVF outcomes in women with non cavity distorting intramural fibroids)


2000 › Publications in medical journals, Abstracts, Book Chapters, Books, & Invited Talks at International Conferences
6th December 2013

36-month study of patient complaints at a tertiary fertility centre.

Robinson L, Cotton J, Sarkar S, Thompson PJ, Coomarasamy A, Rajkhowa M. A Hum Fertil (Camb).  (Epub ahead of print).

1st November 2013

Long gonadotropin-releasing hormone agonist versus short agonist versus antagonist regimens in poor responders undergoing in vitro fertilization: a randomized controlled trial.

Sunkara SK; Coomarasamy A; Faris R; Braude P; Khalaf Y. Fertility and Sterility,

3rd September 2013

Long gonadotropin-releasing hormone agonist versus short agonist versus antagonist regimens in poor responders undergoing in vitro fertilization: a randomized controlled trial.

 Sunkara SK, Coomarasamy A, Faris R, Braude P, Khalaf Y. Fertil Steril. 2013 Nov 1. doi:pii: S0015-0282(13)03109-9. 10.1016/j.fertnstert. [Epub ahead of print].

3rd September 2013

A systematic review and thematic synthesis of qualitative studies on maternal emergency transport in low-and middle-income countries.

 Wilson A; Hillman S; Rosato M; Skelton J; Costello A; Hussein J; MacArthur C; Coomarasamy A. International Journal of Gynecology and Obstetrics, Vol. 122, No. 3, p. 192-201.

17th July 2013

Additional information from chromosomal microarray analysis (CMA) over conventional karyotyping when diagnosing chromosomal abnormalities in miscarriage: a systematic review and meta-analysis.

 Dhillon R; Hillman S; Morris R; McMullan D; Williams D; Coomarasamy A; Kilby M. BJOG.

17th July 2013

Pre-eclampsia is associated with, and preceded by, hypertriglyceridaemia: a meta-analysis.

Gallos I; Sivakumar K; Kilby M; Coomarasamy A; Thangaratinam S; Vatish M. BJOG.

3rd July 2013

The effect of endometriosis on in vitro fertilisation outcome: a systematic review and meta-analysis.

Harb, H; Gallos, I; Chu, J; Harb, M; Coomarasamy, A. BJOG.

16th May 2013

Women's groups practising participatory learning and action to improve maternal and newborn health in low-resource settings: a systematic review and meta-analysis.

Prost A; Colbourn T; Seward N; Azad K; Coomarasamy A; Copas A; Houweling TA ; Fottrell E; Kuddus A; Lewycka S; MacArthur C; Manandhar D; Morrison J; Mwansambo C; Nair N; Nambiar B; Osrin D; Pagel C; Phiri T; Pulkki-Brännström A; Rosato M; Skordis-Worrall J; Saville N; More NS; Shrestha B; Tripathy P; Wilson A; Costello A. Lancet, Vol. 381, No. 9879, p. 1736-46.

1st November 2012

Diagnostic value of serum hCG on the outcome of pregnancy of unknown location: a systematic review and meta-analysis.

 van Mello, N; Mol, F; Opmeer, B; Ankum, W; Barnhart, K; Coomarasamy, A; Mol, B W; van der Veen, F; Hajenius, P. Human Reproduction Update, Vol. 18, No. 6, p. 603-17.

31st October 2012

Should androgen supplementation be used for poor ovarian response in IVF?

 Sunkara SK; Coomarasamy A; Arlt W; Bhattacharya S. Human Reproduction, Vol. 27, No. 3, 01.03.2012, p. 637-640.

1st October 2012

Regression, relapse, and live birth rates with fertility-sparing therapy for endometrial cancer and atypical complex endometrial hyperplasia: a systematic review and meta-analysis.

 Gallos ID; Yap J; Rajkhowa M; Luesley DM; Coomarasamy A; Gupta JK. American journal of obstetrics and gynecology, Vol. 207, No. 4, p. 266.e1-12.

1st October 2012

The effect of sperm DNA fragmentation on miscarriage rates: a systematic review and meta-analysis.

 Robinson L; Gallos ID; Conner SJ; Rajkhowa M; Miller D; Lewis S; Kirkman-Brown J; Coomarasamy A. Human Reproduction, Vol. 27, No. 10, p. 2908-17.

1st September 2012

Prediction of in vitro fertilization outcome at different antral follicle count thresholds in a prospective cohort of 1,012 women.

 Jayaprakasan, K; Chan Y; Islam R; Haoula Z; Hopkisson J; Coomarasamy A; Raine-Fenning N. Fertility and Sterility, Vol. 98, No. 3, p. 657-63.

21st July 2012

Accuracy of single progesterone test to predict early pregnancy outcome in women with pain or bleeding: meta-analysis of cohort studies.

 Verhaegen J; Gallos ID; van Mello NM; Abdel-Aziz M; Takwoingi Y; HarbH; Deeks JJ; Mol BWJ; Coomarasamy A. BMJ, Vol. 345, e6077, 2012.

1st July 2012

Interventions to reduce or prevent obesity in pregnant women: a systematic review.

Thangaratinam S; Rogoziñska E; Jolly C; Glinkowski S; Duda W; Borowiack E; Roseboom T; Tomlinson J; Walczak J; Kunz R; Mol BW; Coomarasamy A; Khan KS. Health Technology Assessment, Vol. 16, No. 31, 07.2012, p. iii-iv, 1-191.

7th January 2012

Effects of interventions in pregnancy on maternal weight and obstetric outcomes: meta-analysis of randomised evidence.

 Thangaratinam S; Rogozinska E; Jolly C; Glinkowski S; Roseboom T; Tomlinson JW; Kunz R; Mol BW; Coomarasamy A; Khan KS. BMJ, Vol. 344, 2012, p. e2088.

9th December 2011

Reproductive outcomes in women with congenital uterine anomalies: a systematic review.

 Chan, Y; Jayaprakasan, K; Tan, A; Thornton, J; Coomarasamy, A; Raine-Fenning, N. Ultrasound in Obstetrics and Gynecology, Vol. 38, No. 4, p. 371-82.

31st October 2011

The prevalence of congenital uterine anomalies in unselected and high-risk populations: a systematic review.

 Chan YY; Jayaprakasan K; Zamora J; Thornton JG; Raine-Fenning N; Coomarasamy A. Human Reproduction Update, Vol. 17, No. 6, p. 761-71.

1st July 2011

Association between the number of eggs and live birth in IVF treatment: an analysis of 400 135 treatment cycles.

Sunkara SK; Rittenberg V; Raine-Fenning N; Bhattacharya S; Zamora J; Coomarasamy A. Human Reproduction, Vol. 26, No. 7, p. 1768-1774.This study was reported in over 200 national and international news media publications, including The Independent, Daily Mail, Virgin Media, CBC News, Times of India and Reuters News.

9th May 2011

Association between thyroid autoantibodies and miscarriage and preterm birth: meta-analysis of evidence.

Thangaratinam S; Tan A; Knox E; Kilby M; Franklyn J; Coomarasamy A. BMJ, Vol. 342, No. may09 1, p. d2616-d2616.This meta-analysis resulted in a £multi-million research award from NIHR/MRC EME, to conduct a multicentre placebo-controlled randomised trial of levothyroxine in euthyroid women with thyroid antibodies awaiting pregnancy conception.

1st January 2011

Does first trimester progesterone prophylaxis increase the live birth rate in women with unexplained recurrent miscarriages?

Coomarasamy A; Truchanowicz E; Rai R. BMJ, Vol. 342, p. d1914.This meta-analysis resulted in a £multi-million research award from NIHR HTA to evaluate the effects of progesterone in preventing miscarriage in women with a history of unexplained recurrent miscarriage, through a multicentre randomised controlled clinical trial.

1st January 2011

Current management of endometrial hyperplasia - a survey of United Kingdom consultant gynaecologists.

Gallos I; Ofinran O; Shehmar M; Coomarasamy A; Gupta J. European journal of obstetrics, gynecology, and reproductive biology, Vol. 158, No. 2, 01.10.2011, p. 305-7.Additional information from array comparative genomic hybridisation (array CGH) technology over conventional karyotyping in prenatal diagnosis - a systematic review and meta-analysis. Hillman S; Pretlove S; Coomarasamy A; McMullan DJ; Davison EV; Maher E; Kilby M. Ultrasound in Obstetrics and Gynecology, Vol. 37, No. 1, p. 6-14.

1st January 2011

A comparison of clinical officers with medical doctors on outcomes of caesarean section in the developing world: meta-analysis of controlled studies.

Wilson A; Lissauer D; Thangaratinam S; Khan K; MacArthur C; Coomarasamy A. BMJ, Vol. 342, d2600.The Birmingham Women’s Hospital and Ammalife are now supporting a training and leadership programme for clinical officers in Malawi and Tanzania (through a £multi-million research project with leadership from the University of Warwick.

1st January 2011

Effectiveness of strategies incorporating training and support of traditional birth attendants on perinatal and maternal mortality: meta-analysis.

Wilson A; Gallos I; Plana N; Lissauer D; Khan K; Zamora J; MacArthur C; Coomarasamy A. BMJ, Vol. 343, d7102.The findings of this meta-analysis have been incorporated into a WHO guideline.

1st January 2011

Gonadotropin-releasing hormone agonists versus antagonists for controlled ovarian hyperstimulation in oocyte donors: a systematic review and meta-analysis.

Bodri D; Sunkara SK; Coomarasamy A. Fertility and Sterility, Vol. 95, No. 1,p. 164-169.

8th October 2010

Oral progestogens vs levonorgestrel-releasing intrauterine system for endometrial hyperplasia: a systematic review and metaanalysis.

 Gallos I; Shehmar M; Thangaratinam S; Papapostolou TK; Coomarasamy A; Gupta J. American journal of obstetrics and gynecology.

1st June 2010

How to interpret randomised trials of test-treatment combinations: a critical evaluation of research on uterine Doppler test to predict, and aspirin to prevent pre-eclampsia.

Fox C; Khan K; Coomarasamy A. BJOG, Vol. 117, No. 7, p. 801-808.

1st June 2010

A systematic review of the effect of oral antioxidants on male infertility.

Ross C; Morriss A; Khairy M; Khalaf Y; Braude P; El-Toukhy T; Coomarasamy A. Reproductive BioMedicine Online, Vol. 20, No. 6, p. 711-723.

1st January 2010

The effect of intramural fibroids without uterine cavity involvement on the outcome of IVF treatment: a systematic review and meta-analysis.

Sunkara SK; Khairy M; El-Toukhy T; Khalaf Y; Coomarasamy A. Human Reproduction, Vol. 25, No. 2, p. 418-29.

1st October 2009

Best evidence continuous medical education.

Raza A; Coomarasamy A; Khan K. Archives of Gynecology and Obstetrics, Vol. 280, No. 4, p. 683-687.

1st August 2009

A review of solutions for diagnostic accuracy studies with an imperfect or missing reference standard.

Reitsma JB; Rutjes AWS; Bossuyt PM; Khan KS; Coomarasamy A. Journal of Clinical Epidemiology, Vol. 62, No. 8, p. 797-806.

1st August 2009

Acupuncture and in vitro fertilization: updated meta-analysis.

Sunkara SK; Coomarasamy A; Khalaf Y; El-Toukhy T. Human Reproduction, Vol. 24, No. 8, p. 2047-2048.

1st January 2009

Estimation of proteinuria as a predictor of complications of pre-eclampsia: a systematic review.

Thangaratinam S; Coomarasamy A; O'Mahony F; Sharp S; Zamora J; Khan K; Ismail K. BMC medicine, Vol. 7, p. 10.

1st January 2009

A multi-centre randomised controlled study of pre--IVF outpatient hysteroscopy in women with recurrent IVF implantation failure: Trial of Out-patient Hysteroscopy - TROPHY in IVF.

El-Toukhy T; Campo R; Sunkara SK; Khalaf Y; Coomarasamy A. Reproductive Health, Vol. 3, No. 6, p. 20.

1st September 2008

A systematic review and meta-analysis of acupuncture in in vitro fertilisation.

El-Toukhy T; Sunkara S K; Khairy M; Dyer R; Khalaf Y; Coomarasamy A. BJOG, Vol. 115, No. 10, p. 1203-1213.

1st June 2008

Tibolone and breast cancer risk: effects of selection bias cannot be eliminated in observational studies.

Coomarasamy, A. BJOG, Vol. 115, No. 7, p. 919.

1st May 2008

Ultrasound-guided hydrosalpinx aspiration during oocyte collection improves pregnancy outcome in IVF: a randomized controlled trial.

Hammadieh N; Coomarasamy A; Ola B; Papaioannou S; Afnan M; Sharif K. Human Reproduction, Vol. 23, No. 5, p. 1113-1117.

18th April 2008

Infertility information on the world wide web: a cross-sectional survey of quality of infertility information on the internet in the UK.

Marriott JV; Stec P; El-Toukhy T; Khalaf Y; Braude P; Coomarasamy A. Human Reproduction, Vol. 23, No. 7, p. 1520-1525.

1st April 2008

The relationship between endometrial thickness and outcome of medicated frozen embryo replacement cycles.

El-Toukhy T; Coomarasamy A; Khairy M; Sunkara SK; Seed P; Khalaf Y; Braude P. Fertility and Sterility, Vol. 89, No. 4, p. 832-9.

11th March 2008

Use of uterine artery Doppler ultrasonography to predict pre-eclampsia and intrauterine growth restriction: a systematic review and bivariable meta-analysis.

Cnossen JS; Morris R; Riet G; Mol BWJ; van der Post JAM; Coomarasamy A; Zwinderman AH; Robson SC; Bindels PJE; Kleijnen J; Khan K. Canadian Medical Association Journal, Vol. 178, No. 6, p. 701-11.This research has achieved 307 citations (Google Scholar).

1st January 2008

Out-patient hysteroscopy and subsequent IVF cycle outcome: a systematic review and meta-analysis.

El-Toukhy T; Sunkara SK; Coomarasamy A; Grace J; Khalaf Y. Reproductive BioMedicine Online, Vol. 16, No. 5, p. 712-9.

1st January 2008

Antral follicle count at down-regulation and prediction of poor ovarian response.

Khairy M; Clough A; El-Touky T; Coomarasamy A; Khalaf Y. Reproductive BioMedicine Online, Vol. 17, No. 4,p. 508-14.

1st January 2008

Selective single blastocyst transfer reduces the multiple pregnancy rate and increases pregnancy rates: a pre- and postintervention study.

Khalaf Y; El-Toukhy T; Coomarasamy A; Kamal A; Bolton V; Braude P. BJOG, Vol. 115, No. 3, p. 385-90.This widely publicised study found that it is possible to reduce the multiple pregnancy rates in IVF treatment without compromising the overall pregnancy rates by selective use of single blastocyst transfer. The paper was extensively publicised by the main-stream media, and is thought have been important in changing policy nationally.

1st January 2008

Tests for predicting complications of pre-eclampsia: a protocol for systematic reviews.

Thangaratinam S; Coomarasamy A; Sharp S; O'Mahony F; O'Brien S; Ismail K; Khan K. BMC pregnancy and childbirth, Vol. 11, p. 8.


Elective delivery in diabetic pregnant women

Coomarasamy A, Gee H. Elective delivery in diabetic pregnant women [letter] Cochrane Database CRG:PREG - Identifier: CD001997


Aspirin has clinically significant benefit in high risk groups

Coomarasamy A, Gee H, Khan KS, Braunholtz D. Summary NNT can mislead clinicians. eBMJ 21.02.2001 (Also simultaneously published in the Cochrane Database - Identifier: CD000492)


How helpful is NHS Direct

Coomarasamy A, Ayuk J. Postal survey of callers [letter] eBMJ 18.04.2000


Investigation and management of the small for gestational age fetus

Coomarasamy A, Fisk N, Gee H, Robson SC. RCOG Green Top Guideline No 31, Nov 2002, RCOG, London.