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An MRCOG lesson on RCTs. A randomised trial is the best design for assessing the effectiveness of a treatment. In this video we look at the 6 methodological features that are important for the quality of an RCT: randomisation; concealment; blinding; ITT; good follow-up rate and comparability of care provided. In Part B, we will look at the statistics of RCTs!

An MRCOG lesson on RCTs: Part B. In part A (please watch that video also!), we learnt about the quality features of an RCT. In this video, we learn about the common statistics we use in the reporting of RCTs. These include: Risk, Relative risk (or Risk Ratio, RR); Absolute risk difference (ARD); and Number Needed to Treat (NNT). We also look at what a Confidence Interval (CI) means. The statistics are illustrated with a simple numerical example. Enjoy!

MRCOG lesson: Renal physiology in pregnancy. What renal function variables go up, go down or remain the same in pregnancy as pre-pregnancy state? And why? What happens to urea, creatinine, glomerular filtration rate and creatinine clearance in pregnancy? Find out from this mini-MRCOG lecture.

Cardiovascular changes in pregnancy for the MRCOG exam. What cardiac variable go up, go down or remain the same in pregnancy compared with the pre-pregnancy state? Why? What are normal cardiac examination and ECG findings in pregnancy? Key MRCOG mini-lecture by Professor Arri Coomarasamy.

Haematological changes in pregnancy for the MRCOG exam. What haematological changes occur during pregnancy? What variables go up, go down or remain the same? Why? A key MRCOG mini-lecture by Professor Arri Coomarasamy.

The PRISM trial is the largest ever randomised trial in miscarriage prevention; it recruited more than 4000 women from 48 hospitals in the UK. It evaluated the effects of progesterone hormone in women with early pregnancy bleeding. Overall, there was a 3% increase in live birth rate with progesterone, compared with placebo, but the finding was associated with some statistical uncertainty (RR 1.03, 95% CI 1.00 to 1.07, p = 0.08). However, a clear benefit was found for women with the dual risk factors of early pregnancy bleeding and a history of (any number of) previous miscarriages (RR = 1.09, [...]

<p>An MRCOG lesson on hereditary gynaecological cancers (BRCA1, BRCA2, RAD51C, RAD51D, BRIP1, Lynch syndrome, Bowden syndrome and Peutz-Jeghers syndrome). An essential lesson for MRCOG.</p>

The Fetal Medicine Foundation webinar, organised by the legend Professor Kypros Nicolaides, was attended by over 7000 delegates from 154 countries. In this lecture, you can hear Professor Arri Coomarasamy discuss the role of progesterone hormone for the prevention miscarriages. What is evidence for effectiveness and safety? What does the totality of evidence, summarised in a meta-analysis show? Which progesterone, what dose, what regimen? This video has the answers! It also covers the two landmark trials on the subject, the PROMISE and PRISM trials, both of which were published in the New England Journal of Medicine. [...]

Contraception after pregnancy in 10 questions and answers: an Essential MRCOG lesson by ACE Courses (www.acecourses.co.uk). Find the answers to many questions around the use of contraception just after child birth, including: when does a women need emergency contraception after childbirth? which emergency contraceptives are safe after childbirth in breastfeeding women? what regular contraceptions are available to breastfeeding women? can combined oral contraceptives be used in breastfeeding women? When can you use copper IUD after childbirth? Can DMPA be used after childbirth?