The Fetal Medicine Foundation webinar, organised by the legend Professor Kypros Nicolaides, was attended by over 7000 delegates from 154 countries. In this lecture, you can hear Professor Arri Coomarasamy discuss the role of progesterone hormone for the prevention miscarriages. What is evidence for effectiveness and safety? What does the totality of evidence, summarised in a meta-analysis show? Which progesterone, what dose, what regimen? This video has the answers! It also covers the two landmark trials on the subject, the PROMISE and PRISM trials, both of which were published in the New England Journal of Medicine.